It is well known that the sugarcane planting material serves as primary source for most of the diseases caused by fungal (red rot, smut, wilt), bacterial (ratoon stunting, leaf scald), viral (mosaic, yellow leaf disease) and phytoplasma (Grassy shoot disease) pathogens. The non-fungal diseases can be inactivated or eliminated through heat treatment or tissue (meristem) culture techniques. However, the fungal pathogens have to be tackled through effective sett treatment with fungicides/ microbes/ other molecules. Our earlier experiments revealed that the effective diffusion of fungicides inside the setts require prolonged duration (overnight) of soaking. Since it is cumbersome to handle huge volume of seed canes for fungicide treatment, ICAR-SBI has developed a technology with prototype (The Patent Office Journal 21/06/2013) to deliver fungicides or beneficial microbes effectively and rapidly in the setts. Based on that technology, the Institute has fabricated bigger sized sett treatment units in collaboration with ICAR-CIAE under DST-IDP project to treat setts with fungicides and other agro inputs for disease management and healthy nursery programme for large scale application. Field trials conducted at the Institute and sugar factories established that effective fungicide delivery through the device has significantly reduced red rot, smut and wilt development from sett and soil borne inocula for 3-4 months in the field. Further in healthy nursery programme, effective treatment of single bud setts with fungicide, insecticide, macro and nutrients benefitted in producing vigorous settlings. This method of sett treatment is an improved method over conventional sett soaking and has several benefits.